When your offering has exceeded its minimum as filed with the SEC, (after your Regulation A+ offering has been Qualified by the SEC), then you are ready to convert the deposits from your investors in Escrow into investments in exchange for shares of your stock. You will notify your investors.
Your transfer agent will hold the shares on the investor's behalf, or transfer the shares to the investors' accounts, according to the investors' wishes.
You are allowed to successive closes until you reach the maximum that was Qualified by the SEC. This process can usually continue for up to 12 months if you file your Form 1-A correctly.